Sialyl lewis
WebJan 21, 2024 · Under conditions of inflammation, epithelial CD44v6 was shown to be decorated with the terminal glycan sialyl Lewis A. Importantly, targeting sialylated Lewis glycans on CD44v6 with a murine antibody GM35 was shown to promote mucosal wound healing in cell lines and in biopsy based wounding assays as well as dextran sodium … Web(1) Led research that identified sialyl Lewis-X as a novel cell surface glycan marker of human hematopoietic stem cells.-- Multi-parameter flow cytometry assays to purify novel subsets of human ...
Sialyl lewis
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WebSialyl Lewis x, Sodium Salt. Synonym(s): Sialyl Lewis x, Sodium Salt. Empirical Formula (Hill Notation): C 31 H 51 N 2 NaO 23. CAS No.: 98603-84-0. Molecular Weight: 842.73. … WebJun 16, 2016 · To improve our understanding of the interaction between SrpA and human platelets, we determined cocrystal structures of the SrpA sialoglycan binding region (SrpA BR ) with five low-affinity ligands: three sialylated trisaccharides (sialyl-T antigen, 3'-sialyllactose, and 3'-sialyl-N-acetyllactosamine), a sialylated tetrasaccharide (sialyl-Lewis ...
WebSialyl-Lewis X C31H52N2O23 CID 643990 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities ...
WebOct 9, 2001 · The interaction of sialyl Lewis x, Lewis x, and α-l-Fuc-(1→3)-β-d-GlcNAc with isolectin A from Lotus tetragonolobus (LTL-A), and with Aleuria aurantia agglutinin (AAA) was studied using NMR experiments and surface plasmon resonance. Both lectins are specific for fucose residues. From NMR experiments it was concluded that α-l-Fuc-(1→3) … WebCD15s (sialyl Lewis x), a tetrasaccharide carbohydrate, is the α2-3 sialylated form of lacto-N-fucopentaose III (CD15) . In addition to eTreg cells and some memory and/or activated T cells, CD15s is highly expressed on …
WebInsulin-like growth factor receptor-1 carrying an uncommon non-sulfated sialyl-Lewis x (sLe x) epitope serves as a distinct P-selectin binding determinant. Several glycosyltransferases, particularly α1,3-fucosyltransferase with rate-limiting activity for sLe x synthesis, are highly expressed in M-CSCs.
Sialyl Lewis (sLeX), also known as cluster of differentiation 15s (CD15s) or stage-specific embryonic antigen 1 (SSEA-1), is a tetrasaccharide carbohydrate which is usually attached to O-glycans on the surface of cells. It is known to play a vital role in cell-to-cell recognition processes. It is also the means by which … See more Sialyl-Lewis X is a tetrasaccharide composed of a sialic acid, fucose and an N-acetyllactosamine. Its systematic name is 5-acetylneuraminyl-(2-3)-galactosyl-(1-4)-(fucopyranosyl-(1-3))-N-acetylglucosamine (Neu5Acα2-3Galβ1 … See more Leukocyte homing Sialyl-Lewis is important in leukocyte tethering and rolling. Leukocytes move through the blood … See more The term Lewis in its name comes from the name of a family of people who suffered from a red blood cell incompatibility. The studies done on these individuals' red blood cells led to the discovery of sialyl Lewis X. Sialyl Lewis x is a very important … See more Leukocyte adhesion deficiency Defective synthesis of the sialyl Lewis antigen results in immunodeficiency (leukocyte adhesion deficiency type 2). Defective synthesis can be caused by the loss of fucosyltransferase, impairing the glycosylation of the … See more • CA19-9 (Sialyl-Lewis A) See more • Chen, G.-Y.; Osada, H.; Santamaria-Babi, L. F.; Kannagi, R. (7 November 2006). "Interaction of GATA-3/T-bet transcription factors regulates expression of sialyl Lewis X homing receptors on Th1/Th2 lymphocytes" See more green mount catholic cemeteryWebMay 31, 2024 · BackgroundLewis antigens such as Sialyl Lewis A (sLeA), Sialyl Lewis X (sLeX), Lewis X (LeX), and Lewis Y (LeY) are a class of carbohydrate molecules that are … greenmount ccWebSialyl Lewis a C31H52N2O23 CID 643993 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities ... fly into ocean city marylandWebrate antigens, sialyl Lewisx (sLex) and sialyl Lewisa (sLea) are involved in colorectal cancer metastasis. METHODS: Metastatic abilities of human colon cancer cell variants that were selected for their high or low cell surface levels of sLex (KM12-HX and KM12-LX, respectively) were analyzed. Also, immunohistochemical expressions of sLex and sLea in … green mount cemetery bath paWeb14 T Loại Phạm vi Tác giả hình không gian Các phát hiện chính T PPP nghiên cứu tối thiểu hóa phạm vi cho việc ra quyết định để đảm bảo tính toàn vẹn của quy trình; giảm thiểu việc cung cấp bảo lãnh, ư[.] - 123doc - thư viện trực tuyến, download tài liệu, tải fly into passionWebJan 14, 2008 · ELAM-1 recognizes the sialyl-Lewis X (sialyl-Lex) determinant, NeuAc alpha 2-3Gal beta 1-4(Fuc alpha 1-3)GlcNAc-, a granulocyte carbohydrate also found on the surface of some tumor cell lines. greenmount cemetery arkansasWebApr 15, 2006 · CLA defines a subset of human peripheral helper memory T cells and has long been used as a specific carbohydrate determinant in characterizing skin-homing helper memory T-cell populations. 5 The HECA-452 antibody defining CLA was shown to recognize the sialyl Lewis X (Le x) determinant, which is known as a typical carbohydrate ligand for ... fly into outer space